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Updating evidence based medicine

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In evidence-based medical guidelines, the conclusions (a.k.a.

recommendations) are marked with different evidence levels according to quality of the supporting evidences.

At nine months, Dynamed had cited 87% of the sampled reviews, while the other summaries had cited less than 50%.

The updating speed of Dynamed clearly led the others.

The cumulative updating rate was analysed with Kaplan-Meier curves.

Results From April to December 2009, 128 reviews were retrieved; 53% (68) from the literature surveillance journals and 47% (60) from the Cochrane Library.

Objective To evaluate the ability of international point of care information summaries to update evidence relevant to medical practice. Setting Top five point of care information summaries (Clinical Evidence, EBMGuidelines, e Medicine, Dynamed, Up To Date) ranked for coverage of medical conditions, editorial quality, and evidence based methodology.

Every month we assessed whether each sampled review was cited in at least one chapter of the five summaries.Evaluation of this process after the completion of the first two reviews resulted in a revised policy statement in 2005 [2], which focused the review process to address questions most relevant to clinicians and scientists. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in adults: an evidencebased review. Currently, seven reviews have been published in on the use of SCT in the therapy of: diffuse large B-cell non-Hodgkin lymphoma (NHL) [3], multiple myeloma (MM) [4], pediatric acute lymphoblastic leukemia (ALL) [5], adult ALL [6], pediatric acute myelogenous leukemia (AML) [7], adult AML [8], and myelodysplastic syndromes (MDS) [9]. For instance, the hazard ratios for citations in EBM Guidelines and Clinical Evidence versus the top performer were 0.22 (95% confidence interval 0.17 to 0.29) and 0.03 (0.01 to 0.05).Conclusions Point of care information summaries include evidence relevant to practice at different speeds.To guide its own activities and that of the expert panels associated with each review, the ASBMT Evidence-Based Review Steering Committee has developed this policy statement regarding the .